The comparison IV (Figure 1A) of n = 26 IDH1-mut astrocytoma versus n = 29 IDH1-mut oligodendroglioma identified 12 significant metabolite changes in the 2-tailed t test (Tables 1 and 2) (carnitine, citrate, ethanolamine, glutathione disulfide, histidine, mannitol, nicotinurate, o-acetylcholine, o-phosphoethanolamine, sarcosine, taurine, and scyllo-inositol). Here, IDH1 is linked to astrocytoma (excluding glioblastoma).