Thyroid hormones play an important physiological role in maintaining blood sugar, controlling appetite, regulating sympathetic nerve activity, energy homeostasis, and metabolism.[22] Hypothyroidism is associated with low energy expenditure and fluid retention, while hyperthyroidism is known to cause weight loss due to increased energy demand.[23,24] Moreover, thyroid dysfunction is accompanied by glucose transport disorder and insulin resistance. This evidence concerns the gene TG and hyperthyroidism.