One-third of FHM1 patients experienced ictal gait ataxia and dysarthria, and 50% of EA2 patients had migraine during the attacks or occurred independently.[4] At the same time, 1 CACNA1A mutation might cause overlapping features, including FHM, epileptic encephalopathy, and EA2 to SCA6 among members of the same family.[5] In this study, all 4 patients carrying CACNA1A I1379F complained of hemiparesis with or without migraine and had never presented with ataxia or encephalopathy. Here, CACNA1A is linked to Encephalopathy.