The result obtained for the time points and type of IFN treatment reduced expression of EGOT, GABPB1-AS1, IDI2-AS1, LINC00312, LINC00662, MIAT, PVT1, SNHG7; expression of these lncRNA was increased in SARS-CoV-2 infected cells or in the tissue obtained from COVID-19 patients. This evidence concerns the gene IDI2 and COVID-19.