It is also important to note that this suppression coincided with modest, but insignificant, increases in the transcript levels of protein kinase C-α (PKC-α), another readout of intermittent hypoxia [59,60], only at LUAD tumor stages 2 (1.44-fold increase; FDR = 0.003) and 3 (1.310-fold increase; FDR = 0.025). The gene discussed is PRKCA; the disease is neoplasm.