Future radiomics trials should enhance the results in the present preliminary study but a real goal would regard in the future the association of MET-PET and MRI images data as demonstrated by Kebir et al. using a semiquantitative approach (T/B ratio) for prediction of isocitrate dehydrogenase (IDH) mutation in classifying glioma [45]. The gene discussed is IDH3A; the disease is glioma.