To determine the frequency of these mutations, we searched the COSMIC database to identify all cutaneous melanoma cases with a GNAQ or GNA11 oncogenic mutation at either Q209 or R183; 2753 and 2295 samples meeting our inclusion criteria (see legend of Supplementary file 2b and c) had GNAQ or GNA11 mutation status reported, respectively. The gene discussed is GNAQ; the disease is cutaneous melanoma.