In contrast, there was no significant up-regulation of any of the genes previously associated with TEAD activation downstream of the non-canonical Hippo pathway in uveal melanoma by Li et al., 2019 (Ctgf, Cyr611, Ankrd1, Pkrcd, Nras, Rras2, Rasgrp1, and Rasgrp3). This evidence concerns the gene RASGRP1 and uveal melanoma.