Another study with glioma and pancreatic cancer cells showed that the use of methyl‐β‐cyclodextrin to deplete cholesterol in cell membranes and destroy lipid rafts resulted in increased extracellular lipid distribution of CD44 and promoted ADAM‐10‐mediated CD44‐associated tumour metastasis.106. This evidence concerns the gene CD44 and familial pancreatic carcinoma.