Furthermore, in a study comparing antemortem 18F-THK5351 PET images and postmortem pathological specimens in a patient with AD, in vivo 18F-THK5351 uptakes were significantly correlated with both the density of tau aggregates in the neocortex and regional MAO-B concentrations in the whole brain (Harada et al. 2018). The gene discussed is MAPT; the disease is Alzheimer disease.