To date, several studies have indicated that histone modifiers and chromatin remodelers, such as protein arginine methyltransferase 1 (PRMT1), jumonji domain containing 1C (JMJD1C), and SWI/SNF related, matrix associated, actin‐dependent regulator of chromatin, subfamily a, member 4 (SMARCA4 also known as BRG1) facilitate the development of AML, including AE‐mediated leukemia.29, 30, 31. This evidence concerns the gene SMARCA4 and acute myeloid leukemia.