SEMA6B and colorectal carcinoma: Meanwhile, upregulated SEMA6B mRNA levels in CRC tissues were also validated in GSE datasets, including GSE41258 (p < 0.001), GSE44076 (p < 0.001), GSE37182 (p < 0.001), GSE20842 (p = 0.003), and GSE83889 (p = 0.015).