MMP9 and thoracic aortic aneurysm: For example, Li and Yang (2018) have identified 1,352 up-regulated and 1,624 down-regulated lncRNAs between thoracic aortic aneurysm and normal thoracic aorta by using lncRNA microarray, and the bioinformatics analysis has revealed that an lnc-RP11-465L10.10 may participate in regulating the transcription of MMP-9, however, the number of samples is not expanded to confirm the accuracy of microarray that would limit the data reliability.