Mu Xu et al. report that lncRNA SNHG6 acts as a molecular sponge of miR-26a/b and miR-214, and releases EZH2 by isolating the endogenous microRNA of CRC cells, which mainly regulates the expression of EZH2 in CRC (Xu et al., 2019a). This evidence concerns the gene EZH2 and colorectal carcinoma.