Among the 18 aberrantly expressed genes in LIHC tissue compared with normal liver tissue (upregulation of CCL5/8/11/13/15/18/20/21/25/26/27/28; downregulation of CCL2/3/4/14/23/24), the transcriptional expression of CCL25, CCL26, and CCL28 were obviously elevated with the aggravation of tumor malignancy while CCL14 was reduced. The gene discussed is CCL2; the disease is neoplasm.