Cell fate-mapping experiments revealed that the majority of NKp46+T-bet+ILCs have a history of RORγt expression, suggesting that Salmonella infection can induce transdifferentiation of NKp46-ILC3s to IFNγ-producing ILC1s (Klose et al., 2013) (Figure 4). The gene discussed is NCR1; the disease is Salmonella Infections.