iNOS contributes to protection against intracellular pathogens such as Toxoplasma gondii (Dunay and Diefenbach, 2018), Listeria monocytogenes (Lu et al., 2015), Mycobacterium tuberculosis (Pahari et al., 2016; Braverman and Stanley, 2017) and Salmonella typhimurium (Yadav et al., 2020), as mice with inactivation of Nos2 gene are highly susceptible to these infections. Here, NOS2 is linked to infection.