The activities of SOD and GSH-Px were elevated in Metformin (p < 0.01, respectively), PDJQ middle-dose (p < 0.05, respectively) and PDJQ high-dose (p < 0.01, respectively) groups compared with the T2DM group, whereas the level of MDA was reduced in Metformin (p < 0.01), PDJQ middle-dose (p < 0.05) and PDJQ high-dose (p < 0.01) groups compared with the T2DM group (Table 4). This evidence concerns the gene SOD1 and type 2 diabetes mellitus.