For instance, the aberrant neutrophil extracellular trap (NET) formation may be involved in the pathogenesis of ILD in DM patients (Peng et al., 2018), and proteinase 3, one type of neutrophil serine proteinases, is lower in patients of DM without ILD (Gao et al., 2018). The gene discussed is PRTN3; the disease is diabetes mellitus.