PLAUR, IL4, COL3A1, CXCL8, MMP2, LOX, MMP14, COL1A2, and PLOD2 were also found to be slightly upregulated in alveolar fibroelastosis and in organizing pneumonia but downregulated in non-specific interstitial pneumonia and usual interstitial pneumonia (Jonigk et al., 2019). This evidence concerns the gene PLOD2 and idiopathic pulmonary fibrosis.