Other studies showed that reduced DAG1 protein expression is associated with poor outcome of colorectal cancer (Coco et al., 2012); downregulation of FN1 decreases proliferation, migration, and invasion of colorectal cancer cells (Cai et al., 2018), while TNC induces EMT and proliferation (Yang et al., 2018). The gene discussed is TNC; the disease is colorectal cancer.