While the DEGs of SP4N cells and CC4N cells were among the tumor related genes (cldn, fn1, twist), transcription factors (eif2s2, eif4e), cycle regulation related genes (cdc25b, cdc20), and energy metabolism (uqcrc2, pfka, ndufs6) (Supplementary Table S4). The gene discussed is EIF4E; the disease is neoplasm.