Of these genes, 11 genes were upregulated (CASP8, NOD1, GPX4, CASP4, PJVK, IL6, IL1B, PLCG1, NOD2, GSDMA, and GSDMC) and 13 genes were downregulated (ELANE, CASP5, NLRP7, IL18, NLRP3, NLRC4, PRKACA, NLRP1, GSDMB, CASP9, CASP3, TIRAP, and NLRP2) between normal and tumor tissues. This evidence concerns the gene NOD2 and neoplasm.