In addition, only six genes (KRT18, ARPC5L, ACTG1, ARPC2, EZR, and YWHAZ) related to pathogenic E. coli infection were simultaneously increased in both GSEA studies; these genes are mostly involved in focal adhesion, as determined via GO analysis (Figures 5F, G). The gene discussed is ACTG1; the disease is escherichia coli infection.