Of those who answered the question, in biochemically euthyroid patients, 46 (49.5%) indicated that treatment with thyroid hormones was never indicated, 44 (47.3%) would consider treatment in case of female infertility with high levels of thyroid peroxidase (TPO) antibodies, and 14 (15.1%) in case of simple goiter growing over time. This evidence concerns the gene TG and endemic goiter.