TP53 and systemic lupus erythematosus: The KEGG pathway annotation for 179 overlapped mRNAs is shown in Figure 5C, and it revealed that immunity (complement and coagulation cascades, hsa04610), infections (pertussis, hsa05133; Staphylococcus aureus infection, hsa05105), inflammation (cytokine–cytokine receptor interaction, hsa05322), immune diseases (systemic lupus erythematosus fiber, hsa05322), formation of fibrous tissue (TGF-beta signaling pathway, hsa04350), cell growth, and death-related pathways (p53 signaling pathway, hsa04115) were highly involved.