GPT and colitis: Indicators of liver function, aspartate aminotransferase (AST/GOT) and alanine aminotransferase (ALT/GPT), and also kidney function, blood urea nitrogen (BUN) and creatinine (CRE), did not differ between MDP5-treated mice and controls on day 11 (Supplementary Figure S2B), suggesting that MDP5 can not only effectively mitigate weight loss and clinical inflammation in a murine colitis model, but also work safely.