However, considering that in these same monkeys the presence of antibodies does not seem to affect the decrease of bacteremia, endotoxemia, CRP, PCT, or the ability for Fh15 to reduce the proinflammatory cytokine/chemokines (Fig. 2), it should not be ruled out that other immunologic factors, unknown so far, could have influenced this result. This evidence concerns the gene CRP and serum lipopolysaccharide activity.