STRING analysis of leading-edge genes (Figure S8D) in these macrophage activation signatures, showed that fatty acid stimulation genes upregulated in MAC-MT in tumor were dominated by metallothionine genes, while inflammatory stimulation genes included several chemokines (CXCL9, CXCL10;Figures 6E and 6F). The gene discussed is CXCL10; the disease is neoplasm.