Interestingly, in NK cells, we observed a significant enrichment of the ‘cytokine-cytokine receptor interaction’ gene set in the CD16neg NK cell subset in tumor compared to normal (Figure 5E) and the leading-edge genes included several chemokine transcripts related to DC recruitment, including CCL5, XCL1, and XCL2 (Figure 5F). This evidence concerns the gene XCL2 and neoplasm.