PTPRC and neoplasm: Since the tight blood vessel barrier impedes the intravasation of tumour cells, we further explored the relationship between vascular VE‐Cad/p120 and CTC count, CTCs were obtained from 5‐ml peripheral blood of included CRC patients, and CK/CD45 biomarkers were used to identify CTCs and white blood cells (WBCs) (Figure 1D).