Addition of IL-15 had no effect on granzyme B expression of α-GalCer treated iNKT cells from SLE patients (55.7±6.2% vs, 50.6±5.5% p = 0.264) but decreased that of controls (44.1±9.9% vs 56.6±9.3% p = 0.013) (Fig 7A). The gene discussed is GZMB; the disease is systemic lupus erythematosus.