PF4 and neoplasm: As shown in Fig 6D, distributions of leukocytes/lymphocytes, identified by Cd45/Cd16/Cd3 staining, appeared similar in the tumors in Dicer1fl/fl/Pf4-Cre and Pf4-Cre mice, indicating that the decreased levels of circulating leukocytes/lymphocytes did not alter their enrichment in the tumor microenvironment.