Endoggresome densities were significantly decreased 2 days after PrPPG14-mCh transfection, in axons from Kif5c−/−, Klc1−/−, and Kif5bpflox/pflox neurons—the latter in a cre-adenovirus multiplicity of infection (MOI) dose-dependent manner—compared to WT hippocampal axons (Fig. 4E and fig. This evidence concerns the gene KLC1 and infection.