The study of ApaI and TaqI to evaluate VDR polymorphisms in nephropathic and non-nephropathic patients with type 2 diabetes conducted by Iranian researchers did not show relationships between the ApaI polymorphism and the nephropathic and non-nephropathic diabetic patients, although it showed significant differences in VDR gene TaqI genotypes of diabetic patients with and without nephropathy .27 This evidence concerns the gene VDR and type 2 diabetes mellitus.