Interestingly, Datura metel L.—a traditional Chinese medicine known to suppress the progression of IMQ‐induced psoriasis in a the mouse model—can suppress TLR7 and TLR8 expression and inhibit the activity of the TLR7/8‐MyD88‐NF‐κB‐NLRP3 inflammasome pathway (Yang et al, 2019). The gene discussed is NFKB1; the disease is psoriasis.