Heatmap showed that PTPN11 was positively more correlated with the NF‐κB pathway in macrophages than dendritic cells from psoriasis lesions (Appendix Fig S17C), suggesting that PTPN11 exacerbates psoriasis mainly in macrophages by activating the NF‐κB pathway. The gene discussed is NFKB1; the disease is psoriasis.