Interestingly, in accordance with the results in the tumor biopsies, in which TRPV2 expression was associated with increased tumor stage, TRPV2 mRNA expression was higher (tenfold increase) in stage IB (EM046 cells) and stage IV (EM012 cells) samples, compared to the stage IA cell lines EM018a and EM033 (Fig. 9A). Here, TRPV2 is linked to neoplasm.