FN1 and esophageal squamous cell carcinoma: This study also found that alcohol consumption, degree of differentiation, depth of infiltration, lymph node metastasis, clinical stage, and Fn-induced CD8+T cells with high expression of KIR2DL1 were independent risk factors affecting the prognosis of ESCC patients, and the 5-year survival rate and median survival time of patients in the positive group were significantly lower than those in the negative group.