PARP1 and myeloid sarcoma: PARP1 activation was neuroprotective against oxidative neuron injury elicited by disrupting the homeostasis of the endogenous antioxidant glutathione,[164] which better reflects in vivo pathophysiology in MS[165] and neurodegenerative disorders[166] compared with primary neurons acutely insulted with high doses of DNA‐damaging agents in vitro.