PARP1 and brain ischemia: Retrospectively, it is notable that most prior publications reporting a cytotoxic role of PARP1 in neuronal death employed male mice for studying the role of PARP1 in cerebral ischemia,[156] Parkinsonism,[162] NMDA‐induced excitotoxicity,[158] and traumatic brain injury.[169] It remains to be defined, however, whether PARP1 deletion or pharmacological inhibition worsens neuropathy in female mice of these experimental models.