The following adjustments were performed in regression models: model 1, crude model; model 2: model 1 + age and sex; model 3, model 2 + BMI, serum albumin, and hemoglobin; model 4, model 3 + phosphorus, PTH, diabetes, hypertension, and cardiovascular disease; model 5, model 4 + eGFR and CRP. The gene discussed is CRP; the disease is hypertensive disorder.