Recently, we demonstrated that the ALDH1A3 isoform was highly and uniquely expressed in mesenchymal glioma stem cells (MES GSCs) and that RNA interference-mediated suppression of ALDH1A3 expression affected the growth of MES GSCs, suggesting ALDH1A3 as a potential target for glioblastoma treatment3. This evidence concerns the gene ALDH1A3 and glioblastoma.