A total of 4085 sepsis admissions were recorded in the MIMIC III database, of which 3030 cases were excluded [age < 18 years (1 case), puerperium (1 case), connective tissue disease (5 cases), hematological disease (7 cases), malignant tumor (12 cases), and no recorded serum albumin level during hospitalization (3004 cases)]. This evidence concerns the gene ALB and connective tissue disorder.