CD4 and HIV infectious disease: Compared two groups of NADCs and ADCs, patients with ADCs were at younger ages when malignancies onsets (39.83 ± 11.56 years vs. 48.33 ± 13.1 years), had shorter term from identification of HIV infection to diagnoses of malignancies (4 months vs. 36 months), lower CD4 counts (104.5/μL vs. 314/μL), and less suppression of HIVRNA (OR 0.23, 95%CI 0.16–0.35).