MKI67 and neoplasm: The results from the H&E staining assay suggested that miR-708 deficiency attenuated the malignancy of tumor cells, and the data from IHC staining for Ki67 showed that the level of Ki67 was decreased in colonic tissues from ApcminmiR-708−/− mice (compared to that in colonic tissues of Apcmin animals), indicating that loss of miR-708 blocked the over-proliferation of colonic cells typically seen in Apcmin mice (Fig. 2c, Fig S2f).