FBXO43 and cholangiocarcinoma: The cell cycle changes in each group were detected using flow cytometry, and the results indicated that compared to the NC group, the number of CCA cells in the G1 phase increased after YY1 and EMI2 were silenced, while the number of CCA cells in the S phase increased after YY1 and EMI2 were overexpressed (Fig. 7F).