CLN5 and myeloid sarcoma: Utilizing qualitative immunofluorescence microscopy, Mandel et al. [19] described CLN-5 staining mainly on B cells, T cells and monocytes from normal human blood, and further detailed by qRT-PCR and Western blotting upregulation of CLN-5 RNA and protein, respectively, in total blood leukocytes from MS patients experiencing relapse.