SOAT1 and hepatocellular carcinoma: An additional study using proteomics data has demonstrated that elevated protein levels of sterol O-acyltransferase 1 (SOAT1)/acyl-coenzyme A:cholesterol acyltransferase 1 (ACAT1), which catalyzes cholesterol esterification, substantially promote malignant phenotypes of HCC cells in vivo and invitro97 (Figure 1).