The differentially expressed genes identified from the hsa_circ_0076931-up-regulated H4 and U118-MG cells were mainly enriched in the TNF signaling pathway, phospholipase D signaling pathway, pathways in cancer, Wnt signaling pathway, PI3K-Akt signaling pathway, proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, chemokine signaling pathway, the cAMP signaling pathway, and cytokine–cytokine receptor interaction (Figure 5D,E). This evidence concerns the gene TNF and cancer.