IFNA1 and infection: While no effect was observed on SARS-CoV-2 in mock- and IBV pre-infected tissues (Figures 4A and B), inhibition of SARS-CoV-2 replication by a concurrent pre-existing infection with RV and IAV (Figures 4C and D) was partially but significantly rescued by IFN neutralization (1.1 and 0.9 log10 fold increase respectively).