CD44 is related to tumor heterogeneous adhesion and other functions, while ITGB1 has been confirmed to be involved in the occurrence and development of gastric, pancreatic, and bladder cancers, and is closely related to cellular immunity and immunosuppression (Guo et al. 2020; Zhuang et al. 2020). The gene discussed is ITGB1; the disease is urinary bladder carcinoma.