CD177 (depression), RHD (dyskinesia), PYGL (UPDRS part 4) and STK4 (Hoehn and Yahr) reached significance when clumping at \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$${r}^{2}=0.001$$\end{document}r2=0.001. The gene discussed is RHD; the disease is major depressive disorder.