SOX6 and neoplasm: The results revealed that the sizes of tumors were significantly reduced at both 2- and 3-weeks post-injection under cisplatin treatment in PBS group, whereas the reduced tumor sizes under cisplatin treatment were significantly lower in Dox-treated group than that in PBS-treated group, indicating that SOX6 could significantly reduce the chemosensitivity of xenograft to cisplatin (Fig. 5F and Supplementary S8B–G).