Analysis of schizophrenia subjects according to the presence or absence of antipsychotic treatment, revealed that ADRA2C mRNA expression was non-significantly enhanced over that in controls in both AP-free (Δ = +53%, n = 9, p = 0.136, Fig. 1B) and AP-treated schizophrenia subjects (Δ = +54%, n = 8, p = 0.088, Fig. 1B). Here, ADRA2C is linked to schizophrenia.