Real-time PCR analysis showed that after the AD model was established, compared with that in the vehicle (PBS-treated) group, the expression of IL-17α, IL-6, and IL-33 mRNA in the Muse cell group was significantly decreased in the spinal cord, while the spinal-released cytokine IL-1β was not different between the two groups (Fig. 2B). Here, IL1B is linked to Alzheimer disease.